Sedating antihistamine list

In severe allergies, such as anaphylaxis or angioedema, these effects may be of life-threatening severity.Additional administration of epinephrine, often in the form of an autoinjector, is required by people with such hypersensitivities.-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition.However, some second-generation antihistamines, notably cetirizine, can interact with CNS psychoactive drugs such as bupropion and benzodiazepines.-antihistamines are second-generation antihistamines informally labeled third-generation because the active enantiomer (levocetirizine) or metabolite (desloratadine and fexofenadine) derivatives of second-generation drugs are intended to have increased efficacy with fewer adverse drug reactions.Fexofenadine is associated with a lower risk of cardiac arrhythmia compared to terfenadine.The most common adverse effect is sedation; this "side-effect" is utilized in many OTC sleeping-aid preparations.Other common adverse effects in first-generation H-antihistamines include dizziness, tinnitus, blurred vision, euphoria, uncoordination, anxiety, increased appetite leading to weight gain, insomnia, tremor, nausea and vomiting, constipation, diarrhea, dry mouth, and dry cough.

Furthermore, essentially the same proportion of patients reported no benefit from either type of treatment."-receptor and their ability to cross the blood-brain barrier.Over-the-counter (OTC) antihistamines can help treat symptoms such as: First-generation OTC oral antihistamines, including diphenhydramine and chlorpheniramine, are the oldest group.They are sedating, which means they’re likely to make you drowsy after you use them.The second-generation H receptors and cholinergic receptors.This selectivity significantly reduces the occurrence of adverse drug reactions, such as sedation, while still providing effective relief of allergic conditions.

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